diff --git a/setup.py b/setup.py
--- a/setup.py
+++ b/setup.py
@@ -595,6 +595,16 @@ for plat, func in [('bsd', 'setproctitle
     if re.search(plat, sys.platform) and hasfunction(new_compiler(), func):
         osutil_cflags.append('-DHAVE_%s' % func.upper())
 
+for plat, header in [
+    ('bsd|darwin|linux', 'sys/mount.h'),
+    ('bsd|darwin|linux', 'sys/param.h'),
+    ('linux', 'linux/magic.h'),
+    ('linux', 'sys/vfs.h'),
+]:
+    if re.search(plat, sys.platform) and hasheader(new_compiler(), header):
+        macro = header.replace('/', '_').replace('.', '_').upper()
+        osutil_cflags.append('-DHAVE_%s' % macro)
+
 if sys.platform == 'darwin':
     osutil_ldflags += ['-framework', 'ApplicationServices']